Neuregulin-1 elicits a regulatory immune response following traumatic spinal cord injury
نویسندگان
چکیده
منابع مشابه
Heterotopic ossification following traumatic brain injury and spinal cord injury.
Heterotopic ossification associated with neurologic injury, or neurogenic heterotopic ossification, tends to form at major synovial joints surrounded by spastic muscles. It is commonly associated with traumatic brain or spinal cord injury and with other causes of upper motor neuron lesions. Heterotopic ossification can result in a variety of complications, including nerve impingement, joint ank...
متن کاملPOST-TRAUMATIC CHRONIC SPINAL CORD INJURY: ASSESSMENT WITH MRI
The initial experience concerning the use of magnetic resonance imaging in 94 patients who had sustained chronic cord injury showed its specific advantages over traditional imaging modalities. A variety of 84 cord abnormalities were identified including myelomalacia in 47%, cord cysts in 37%, focal atrophy in 11 % and cord transection in 5%. Canal stenosis was seen in twenty-five patients, ...
متن کاملMicroRNA Dysregulation in the Spinal Cord following Traumatic Injury
Spinal cord injury (SCI) triggers a multitude of pathophysiological events that are tightly regulated by the expression levels of specific genes. Recent studies suggest that changes in gene expression following neural injury can result from the dysregulation of microRNAs, short non-coding RNA molecules that repress the translation of target mRNA. To understand the mechanisms underlying gene alt...
متن کاملEffect of chondroitinase ABC on inflammatory and oxidative response following spinal cord injury
Objective(s): Chondroitinase ABC (cABC) treatment improves functional recovery following spinal cord injury (SCI) through degrading inhibitory molecules to axon growth. However, cABC involvement in other pathological processes contributing to SCI remains to be investigated. Here, we studied the effect of cABC I on oxidative stress and inflammation developed in a rat model of SCI.Materials and M...
متن کاملThe early evolution of spinal cord lesions on MR imaging following traumatic spinal cord injury.
BACKGROUND AND PURPOSE How early spinal cord injury (SCI) lesions evolve in patients after injury is unknown. The purpose of this study was to characterize the early evolution of spinal cord edema and hemorrhage on MR imaging after acute traumatic SCI. MATERIALS AND METHODS We performed a retrospective analysis of 48 patients with clinically complete cervical spine injury. Inclusion criteria ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Neuroinflammation
سال: 2018
ISSN: 1742-2094
DOI: 10.1186/s12974-018-1093-9